Decoding Detoxification Through Genetic SNPs And Lab Testing

Ep 79
This week on ReInvent Healthcare, I emphasize the importance of understanding certain genetic variants and their impact on detoxification pathways. As well as certain tests you can suggest to your clients and foods that can help their detoxification pathways so they live a balanced lifestyle.


Defining Detoxification Pathways
Detoxification is a critical function, especially in today’s world filled with environmental toxins, pesticides, and pollutants. The liver plays a crucial role in detoxification, and there are two phases of detoxification – Phase 1 and Phase 2. Understanding genetic SNPs (single nucleotide polymorphisms) and their role in the body’s detox pathways give us valuable insights into individual variations and susceptibilities.

Some Detoxification SNPs – There are several genetic SNPs related to detoxification pathways, such as CYP1A1, CYP1A2, CYP1B1, CYP3A4, CYP2C9, and others. These SNPs influence the detoxification of environmental toxins, caffeine, estrogen, prescription drugs, aflatoxin, and more. Understanding these SNPs allows us to identify potential imbalances in detox pathways and helps us make informed decisions for personalized wellness strategies.

Importance of Testing
Testing is essential to determine whether the detoxification SNPs are active and causing imbalances in the detox pathways. Organic acid tests and blood tests, such as liver function tests and methylation markers, can help identify potential issues. By combining genetic information with lab testing, we gain a comprehensive view of a person’s detoxification capabilities. Understanding genetic SNPs and lab results helps us guide patients toward avoiding toxic exposures, environmental pollutants, and food additives that may burden their detox pathways.

How To Support Detoxification
Once genetic SNPs and active detox pathways are identified, our clients can be educated on avoiding toxic substances and making lifestyle changes. These changes may include using non-toxic household products, choosing organic food, avoiding food additives, and reducing exposure to common allergens. Additionally, incorporating certain detox-supporting herbs like artichoke leaf, burdock root, dandelion, and Hawthorn berry can be beneficial.



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Ritamarie Loscalzo

Dr. Ritamarie Loscalzo is a best-selling author and speaker known for her extensive knowledge, infectious energy, and inspirational message that encourages individuals to become their own best health advocate. She is an internationally recognized nutrition and health authority who specializes in using the wisdom of nature to restore hormone balance with a special emphasis on thyroid, adrenal and insulin imbalances. She founded the Institute of Nutritional Endocrinology to empower health and nutrition practitioners to get to the root cause of health concerns by using functional assessments and natural therapeutics to balance the endocrine system, the body's master controller.

Dr. Ritamarie is a licensed Doctor of Chiropractic with Certification in Acupuncture and is a Diplomat of the American Clinical Nutrition Board. She is a Certified Clinical Nutritionist with a Master’s in Human Nutrition, has completed a 2-year, 500-hour Herbal Medicine Program at David Winston’s Center for Herbal Studies and has a master's degree in Computer Science, which contributes to her skills as an ace problem solver.