Functional Medicine and APOE: Keys to Cardiovascular and Alzheimer’s Prevention

Ep 86
This week on ReInvent Healthcare, I talk about the importance of the Apolipoprotein E (APOE) in health and disease as well as the significance of individualized approaches to health based on genetics, lifestyle, and risk factors.


Apolipoprotein E (APOE) Importance
APOE is a protein that plays a central role in lipid metabolism, neurobiology, and is implicated in the development of neurodegenerative diseases such as Alzheimer’s. 

APOE is a critical factor to consider when assessing your client’s risk for cardiovascular disease and Alzheimer’s. Understanding the significance of APOE in these contexts is essential for tailoring effective health improvement strategies.

Genetic Variants of APOE and Their Implications
APOE can exist in different genetic variants, including APOE2, APOE3, and APOE4. These variants have varying effects on the client’s risk for diseases like Alzheimer’s and cardiovascular disease. 

APOE4, in particular, is associated with a higher risk, while APOE2 is considered protective. Understanding a person’s APOE genetic makeup is crucial for tailoring lifestyle and dietary recommendations.

Individualized Approaches to Health and Risk Reduction
Individualized approaches to health based on genetics, lifestyle, and risk factors are important. It highlights the role of diet, particularly cautioning against certain diets like high-saturated fat diets for individuals with APOE4 variants. 

These personalized strategies empower clients to proactively manage their health and mitigate potential risks.

ReInvent Healthcare Links

Ep 86 QC 1
Ep 86 QC 2

Listen on your favorite podcast platform!

Share This Episode

Ritamarie Loscalzo

Dr. Ritamarie Loscalzo is a best-selling author and speaker known for her extensive knowledge, infectious energy, and inspirational message that encourages individuals to become their own best health advocate. She is an internationally recognized nutrition and health authority who specializes in using the wisdom of nature to restore hormone balance with a special emphasis on thyroid, adrenal and insulin imbalances. She founded the Institute of Nutritional Endocrinology to empower health and nutrition practitioners to get to the root cause of health concerns by using functional assessments and natural therapeutics to balance the endocrine system, the body's master controller.

Dr. Ritamarie is a licensed Doctor of Chiropractic with Certification in Acupuncture and is a Diplomat of the American Clinical Nutrition Board. She is a Certified Clinical Nutritionist with a Master’s in Human Nutrition, has completed a 2-year, 500-hour Herbal Medicine Program at David Winston’s Center for Herbal Studies and has a master's degree in Computer Science, which contributes to her skills as an ace problem solver.