Demystifying Methylation and Epigenetics

Dr Ritamarie Loscalzo
In this week’s episode of ReInvent Healthcare, we continue our discussion on epigenetics, and the importance of the terms methylation and epigenetics in the nutrigenomics world. Most people really don't understand what they are, and as a practitioner you need to be able to explain these terms to your clients in ways that make sense to them. Tune in to learn how to let your clients know the significance of epigenetic and methylation to the health challenges that they're coming to you to resolve.


  • [03:00] As with genes, epigenetic factors can be passed on from parent to child.

  • [10:00] Explaining the SNPs associated with B12

  • [13:00] CBS takes the homocysteine down into the sulfation pathways where glutathione is made. If there’s a block in the CBS, we can get an elevation in homocysteine.

  • [16:00] Under methylation can lead to low levels of serotonin and, as a result, depression. Over methylation can cause symptoms like anxiety and panic attacks.

  • [18:00] The importance of diet and lifestyle, not just nutritional supplements.

  • [22:00] We are here to support our clients to get better.


  • It’s important to assist your clients in understanding epigenetics and how their day to day activities affect the expression of their genes.

  • It’s best to consider diet and lifestyle factors, not just nutritional supplements, when it comes to SNPs in methylation


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Ritamarie Loscalzo

Dr. Ritamarie Loscalzo is a best-selling author and speaker known for her extensive knowledge, infectious energy, and inspirational message that encourages individuals to become their own best health advocate. She is an internationally recognized nutrition and health authority who specializes in using the wisdom of nature to restore hormone balance with a special emphasis on thyroid, adrenal and insulin imbalances. She founded the Institute of Nutritional Endocrinology to empower health and nutrition practitioners to get to the root cause of health concerns by using functional assessments and natural therapeutics to balance the endocrine system, the body's master controller.

Dr. Ritamarie is a licensed Doctor of Chiropractic with Certification in Acupuncture and is a Diplomat of the American Clinical Nutrition Board. She is a Certified Clinical Nutritionist with a Master’s in Human Nutrition, has completed a 2-year, 500-hour Herbal Medicine Program at David Winston’s Center for Herbal Studies and has a master's degree in Computer Science, which contributes to her skills as an ace problem solver.